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Information × Registration Number 0225U002157, (0122U000333) , R & D reports Title To develop technology for removal of intramedullary tumors using intraoperative neuromonitoring popup.stage_title Розробити технологію видалення інтрамедулярних пухлин із застосуванням інтраопераційного нейромоніторингу Head Slynko Yevhen І., д.мед.н. Registration Date 21-02-2025 Organization The State Institution "Romodanov Neurosurgery Institute, National Academy of Medical Sciences of Ukraine" popup.description1 Improving the effectiveness of surgical treatment of patients with intramedullary tumors of the spinal cord, reducing the number of postoperative complications, improving quality of life and reducing disability of patients popup.description2 Report on the GDR: 90 pp., 4 tables, 50 figures, 61 sources. INTRAMEDULLARY TUMORS OF THE SPINAL CORD, SURGICAL TREATMENT, INTRAOPERATIVE NEUROMONITORING The pathogenetic mechanisms of intracerebral tumors were investigated. Structural and ultrastructural types of intracerebral tumors were established using light-optical, immuno-histochemical, and ultrastructural methods. The genetic features of intracerebral tumors were established using genetic research methods. The peculiarities of the local and general progression of the tumor process, depending on the primary origin of the tumor, its pathohistological type, structural features, and genetic markers, have been clarified. n the basis of light-optical, immunohistochemical, ultrastructural methods, genetic studies, dynamic MRI, CT, scintigraphic, positron emission (PNET) studies, the peculiarities of the biological behavior of intracerebral tumors have been established. umor removal techniques with intraoperative monitoring of spinal cord functions have been implemented. The specific contribution of the radicality of surgical intervention with the use of intraoperative monitoring, radiation and chemotherapeutic treatment on the local and general progression of the tumor process of intracerebral tumors has been clarified. According to radiological examination, the criteria for preoperative diagnosis of tumor growth variants and its pathohistological type have been established. Surgical approaches have been developed, taking into account the type of tumor growth - posterior middle myelotomy, posterior intermittent myelotomy, myelotomy along the posterior REZ (zone of entry into the brain of the posterior roots), anterior-middle and anterior REZ (along the front zone of entry into the brain of the roots), myelotomy in the zone of exophytic exit of the tumor.   Product Description popup.authors Vaslovych Viktoriia V. Derkach Yurii V. Levcheniuk Sofiia V. Malysheva Tetiana A. Nekhlopochyn Oleksii S. Robak Oleh P. Slynko Yevhen І. popup.nrat_date 2025-02-21 Close