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Information × Registration Number 0225U002284, (0122U001490) , R & D reports Title To study the structural and functional changes of the retina and choroid in patients with dystrophic and post-inflammatory diseases of the retina and choroid after laser and antiangiogenic therapy popup.stage_title Вивчити структурні та функціональні зміни сітківки та судинної оболонки у пацієнтів з дистрофічними та післязапальними захворюваннями сітчастої та судинної оболонок після лазерної та антиангіогенної терапії Head Pasiechnikova Nataliia V., Доктор медичних наук Registration Date 28-02-2025 Organization VP Filatov Institute of Ophthalmology and Tissue Therapy of the National Academy of Medical Sciences of Ukraine popup.description1 To study the dynamics of structural and functional parameters of the retina and choroid in patients with dystrophic and post-inflammatory diseases of the retina and choroid after laser and antiangiogenic therapy. popup.description2  Scientific data have been updated to show that exposure of retinal pigment epithelial cells to laser radiation with a wavelength of 577 nm in the micro-pulse mode using 50 % of the threshold power helps to restore the retinal structure by preventing the accumulation of subretinal fluid in patients with chronic central serous chorioretinopathy, resulting in complete or partial regression of subretinal fluid in 93 % of cases during the follow-up period of 6 months. For the first time, it was found that antiangiogenic therapy in the pro re nata regimen induces a therapeutic pathomorphosis of subretinal neovascularization in central chorioretinitis and retinal angioid streaks, resulting in improved visual acuity due to the regression of neovascularization vessels and restoration of retinal structure during the follow-up period of 48 weeks. The scientific data on the severity of ciliary body damage by the transscleral effect of laser radiation with a wavelength of 810 nm with various energy parameters in the experiment were supplemented. Thus, selective ciliary epithelium damage is achieved with a power of 1000 mW with an exposure of 1.5 s (energy 1.5 J) and is accompanied by minimal disorganization of the architecture and preservation of the stroma of the ciliary body of rabbits. Gross damage to the ciliary body and sclera is observed when the laser power is increased to 2000 mW with an exposure of 1.5 s (energy 3.0 J). Product Description popup.authors Huzun Olha V. Zadorozhnyi Oleh S. Korol Andrii R. Kustryn Taras B. Nasinnyk Illia O. Nevska Alla O. Chechyn Petro P. popup.nrat_date 2025-02-28 Close