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Information × Registration Number 0225U002308, (0122U001205) , R & D reports Title To study clinical, functional and structural-morphological patterns of bronchopulmonary system damage in victims of the Chernobyl accident in the remote post-accident period and to determine the risks of complications popup.stage_title Визначити закономірності розвитку клінічних, функціональних та структурно-морфологічних порушень стану бронхолегеневої системи та ризики розвитку ускладнень у віддаленому післяаварійному періоді в осіб, які зазнали впливу іонізуючого випромінювання Head Shvaiko Liudmyla I., Доктор медичних наук Registration Date 03-03-2025 Organization State Institution "National Research Center for Radiation Medicine, Hematology and Onkology of the National Academy of Medical Sciences of Ukraine" popup.description1 Тo determine the patterns of clinical, functional and structural-morphological lesions in the bronchopulmonary system and the risks of complications in the remote post-accident period in persons exposed to ionizing radiation popup.description2  Object: the bronchopulmonary system state of clean-up workers of the Chornobyl NPP accident. Aim: to determine the patterns of clinical, functional and structural-morphological signs of the bronchopulmonary system damage and the risks of complications developing in the remote post-accident period in persons exposed to ionizing radiation. Methods: generally accepted clinical and laboratory examination methods, pulmonary functional tests, spiral computed tomography of the chest, determination of sleep apnea-hypopnea using the SOMNOcheck micro device, statistical methods. The main clinical and functional patterns of COPD in clean-up workers of the Chornobyl NPP accident were determined: rapidly progressive course, slowly progressive course, PRISm. The rapidly progressive pattern of COPD was most frequently recorded in clean-up workers of the Chornobyl NPP accident and was characterized by a significant deterioration in intrathoracic pressure and lung diffusion capacity, a higher frequency of obstructive sleep apnea, cardiovascular diseases, and was significantly more common in clean-up workers of the “iodine period” (26.04‒15.05.1986 yy). Risk factors for the development of ventilation, and subsequently respiratory failure and a significant deterioration in the quality of life, an increase in socio-economic losses to society in clean-up workers of the Chornobyl NPP accident, COPD patients, are a rapid decrease in lung volume tests, an increase in lung reserve volumes and a decrease in lung diffusion capacity, a significant progression of emphysematous, fibrotic and sclerotic changes, a decrease in tolerance to physical exertion during dynamic observation. Based on the results of the research, 6 scientific papers were published, 1 report was made at an international scientific forum, and a new technology was presented. Product Description popup.authors Bazyka Kostiantyn D. Savchenko Alisa A. Sushko Viktor O. Shvaiko Liudmyla I. Shylenko Mariia V. popup.nrat_date 2025-03-03 Close