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Information × Registration Number 0225U002722, (0122U200159) , R & D reports Title Profiles and functional role of metabolites of bacteria of the genera Bacillus and Pseudomonas popup.stage_title Визначення метаболічних профілів штамів бактерій роду Bacillus – продуцентів пігментів, антибіотичних сполук, ферментів Head Avdieieva Liliia V., Доктор медичних наук Registration Date 01-04-2025 Organization Institute of Microbiology and Virology. D.K. Zabolotny National Academy of Sciences of Ukraine popup.description1 Based on the obtained metabolic profiles of bacteria of the genera Bacillus and Pseudomonas to determine the functional role of their metabolites popup.description2  73 endometabolites of the P. endophytica UKM B-5715 strain were identified, belonging to 30 subclasses of organic compounds. Amino acids were the most abundant. Despite the qualitative similarity of the two nutrient media, King A medium was found to be more suitable for the biosynthetic activity of the P. endophytica UKM B-5715 strain. A protocol for determining the metabolic profiles of microorganisms during their cultivation in both mono- and mixed cultures was developed. It was established that the B. velezensis IMV B-7571 strain exhibits strong antagonistic activity against conditionally pathogenic and ichthyopathogenic microorganisms. The active substances in the lysate of P. aeruginosa UKM B-333 are pyocins of the S1 and S5 subtypes. Only pyocins of the S5 subtype exhibit activity against phytopathogenic bacteria Pseudomonas syringae. Product Description popup.authors Avdieieva Liliia V. Balko Oleksandr B. Balko Olha I. Boretska Kateryna Ye. Hospodarenko Rymma A. Hrabova Hanna Yu. Direnko Dmytro I. Drahovoz Ihor V. Klochko Vitalii V. Kozyreva Valentyna O Korzh Yuliia V. Mozhaieva Larysa L. Okhota Olha A. Poberezhna Liudmyla M. Poliakova Alina V. Rybalchenko Nataliia P. Kharkhota Maksym A. Kharchuk Maksym S. Chuiko Nelia V. Yaroshenko Liudmyla V. popup.nrat_date 2025-04-01 Close