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Information × Registration Number 0225U002728, (0124U001558) , R & D reports Title Participation of stress-reactive systems in the development of local and systemic pathological processes and tissue regeneration. popup.stage_title Дослідження участі стресреактивних систем у розвитку місцевого запального процесу і тканинної регенерації при термічній травмі і пошкодженні органів дихання. Head Portnichenko Volodymyr I., Доктор медичних наук Registration Date 01-04-2025 Organization Bogomolets Institute of Physiology of the National Academy of Sciences of Ukraine popup.description1 Establishing the mechanisms of the participation of stress-reactive systems in the course of processes of systemic and local inflammation on experimental models of burns and pneumonia, as well as the development of new therapeutic agents and methods of therapy based on melatonin, cerium nanoparticles and a complex of microbial enzymes (KEP) to increase the effectiveness of the correction of these lesions. popup.description2  An experimental model was created to study the influence of stress-reactive systems on local inflammation processes in thermal skin injury and respiratory system damage in laboratory Wistar rats. The study of the burn injury model in rats showed that as a result of skin tissue damage and pain stress, both a local reaction and a general reaction of the animal's body are observed. The obtained data are of scientific and practical importance for finding optimal ways of correction and acceleration of the rate of physiological and reparative regeneration of connective tissue in thermal injury. Product Description popup.authors Zavhorodnyi Mykola O. Kolomiiets Iryna I. Litovka Iryna H. Levashov Mykhailo I. Portnichenko Volodymyr I. Safonov Serhii L. Tsapenko Petro K. Yanko Roman V. popup.nrat_date 2025-04-01 Close