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Information × Registration Number 0225U003542, (0119U100621) , R & D reports Title Peculiarities of formation of allergic and autoimmune diseases in children and possibilities of their prevention and treatment popup.stage_title Особливості формування захворювань алергічного та автоімунного генезу у дітей різного віку та можливості їх профілактики і лікування Head Okhotnikova Olena M., Доктор медичних наук Registration Date 11-07-2025 Organization Shupyk National Healthcare University of Ukraine popup.description1 Improving the effacacy of medical care for children with allergic and autoimmune pathology by identifying the features of immune status and the level and spectrum of specific sensitization in allergic diseases, developing indications for prescribing, and determining the efficacy and safety of treatment with medicamеntal and non-medicamental methods. popup.description2  It was found that the allelic polymorphism of pro-inflammatory cytokine genes leads to a change in their function and contributes to the development and unfavorable course of juvenile arthritis. A significant relationship was found between the frequency of adverse outcomes in juvenile idiopathic arthritis and the IL-6 GC gene variant. Regarding the G308A gene variant, heterozygotes (GA) were more frequently patients with seropositive rheumatoid factor polyarthritis and systemic arthritis. Product Description popup.authors popup.nrat_date 2025-07-11 Close