Search academic texts

Information × Registration Number 0225U003879, (0122U201372) , R & D reports Title 645. Elaboration of antimicrobial biomaterials on the base of natural biopolymers and quaternary ammonia compounds popup.stage_title Розробка ефективного складу та технології виготовлення антимікробних біоматеріалів на основі біополімерів та четвертинних амонієвих сполук. Head Oleksandr A. Hruzevskyi, Доктор медичних наук Registration Date 05-09-2025 Organization Odessa National Medical University popup.description1 Determination of physicochemical and antimicrobial properties of new antimicrobial biomaterials developed on the basis of quaternary ammonium compounds under experimental conditions. popup.description2  The composition and technology of production of antimicrobial biomaterials based on biopolymers and quaternary ammonium compounds have been developed. Samples of polymer antimicrobial compositions with varying qualitative content have been prepared. Primary microbiological screening of antimicrobial activity of the developed agents against reference and clinical strains of microorganisms has been carried out. The spectrum of antimicrobial action of selected biomaterial compositions, based on primary screening results, has been determined using reference and clinical strains of different microorganisms. Clinical isolates of microorganisms known to participate in the development of healthcare-associated infections (HAIs) and exhibiting multidrug resistance have been obtained. Etiologically significant strains of microorganisms have been identified. The susceptibility of contemporary wound pathogens to the new antimicrobial biomaterial has been studied. The susceptibility of planktonic and biofilm forms of reference and clinical strains of A. baumannii, E. coli, K. pneumoniae, and S. aureus to the tested antiseptics has been investigated. Antibiotic resistance of clinical strains and their biofilm-forming ability have been studied. Product Description popup.authors Denysko Tetiana V. Dubina Anzhela V. Kahliak Mariia D. Kobylnyk Snizhana M. Koltsova Iryna H. popup.nrat_date 2025-09-05 Close