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Information × Registration Number 0225U004529, (0123U100060) , R & D reports Title Peculiarities of metabolic processes under the action of exogenous toxicants and in conditions of pathology popup.stage_title Особливості метаболічних процесів за дії екзогенних токсикантів та в умовах патології Head Fira Liudmyla S., д.б.н. Registration Date 10-12-2025 Organization Ternopil National Medical University named after I. Gorbachevsky of the Ministry of Health of Ukraine popup.description1 To investigate the mechanisms of metabolic disorders under the conditions of exogenous toxicants entering the body and the development of pathological conditions, to find effective schemes for correcting the identified disorders. popup.description2 Research report: 118 pages, 23 figs., 21 tables., 3 forms., 130 references. Keywords: colorectal cancer, drug-induced hepatitis, obesity, antiphospholipid syndrome, metabolic syndrome, exogenous toxicants, herbal medicines. Relevance of the topic. The study of the impact of exogenous toxicants on a living organism is due to the significant distribution of these compounds in the environment, their stability, high ability to accumulate in biosphere objects, ease of inclusion in the main food chains and the risk of accumulation in the body in significant quantities. This issue has become especially acute today, when there is intensive development of new technologies, which leads to an increase in the level of interaction of exogenous toxicants with bioobjects. Modern man is exposed to the simultaneous influence of several toxic factors, which leads to the development of multi-organ pathology and functional disorders of internal organs. The problem of the combined effect of toxicants of various nature is one of the most relevant in modern medicine. The object of the study is biochemical and morphological changes in biological objects caused by exogenous toxicants of various nature, as well as in the development of multi-organ pathology. The purpose of the work is to investigate the mechanisms of metabolic disorders under the conditions of exogenous toxicants entering the body and in the development of pathological conditions, to find effective schemes for correcting the identified disorders and to conduct preclinical studies of drugs. Research methods are biochemical, biophysical, histological (light-optical and electron microscopic), histochemical, toxicological, statistical. Product Description popup.authors popup.nrat_date 2025-12-10 Close