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Information × Registration Number 0225U004534, (0124U004381) , R & D reports Title Genetic control of pentose sugars transport and metabolism during alcoholic fermentation in Ogataea polymorpha yeast popup.stage_title Посилення експресії генів, що потенційно можуть виконувати роль транспортерів пентоз, та вивчити фенотип отриманих трансформантів. Ідентифікація генів, що забезпечують ріст дріжджів O polymorpha на L-арабінозі як єдиному джерелі вуглецю шляхом секвенування геномів відповідних штамів. Head Sibirny Andrii A., проф. Registration Date 10-12-2025 Organization Institute of Cell Biology of the National Academy of Sciences of Ukraine popup.description1 Identification of regulatory genes involved in the metabolism of major pentose sugars (D-xylose, L-arabinose), as well as improving the efficiency of pentose transport in thermotolerant yeast Ogataea polymorpha through metabolic engineering approaches. popup.description2 The main research objective of this proposal is identification of the regulatory genes involved in metabolism of the major pentose sugars (D-xylose, L-arabinose) in the thermotolerant yeast O. polymorpha. Xylose and L-arabinose are important components of renewable feedstocks (lignocellulose and pectin) for biofuel production, being the second and third sugars by abundance in nature. However, since L-arabinose and xylose are not utilized as carbon sources by most known yeast strains, a significant percentage of total carbon in the production of bioethanol from plant residues is not used. Moreover, despite significant efforts made in the field of alcoholic fermentation of basic sugars from lignocellulose hydrolysates and some achievements in this field (especially on xylose fermentation), yeast strains capable of efficient fermentation of L-arabinose have not been yet identified. Product Description popup.authors Kostyantyn V. Dmytruk Vasylyshyn Roksolana V. popup.nrat_date 2025-12-10 Close