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Information × Registration Number 0225U005103, (0125U001427) , R & D reports Title Study on the molecular and genetic mechanisms regulating PAI-1 expression under hyperosmotic stress. popup.stage_title Дослідження механізму 4G/5G-заоежної експресії PAI-1 у відповідь на гіперосмотичний стрес на моделі in vitro Head Yatsenko Tetiana A., Кандидат біологічних наук Registration Date 25-12-2025 Organization Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine popup.description1 The aim of this project is to identify signaling pathways and determine the role of transcription factors that regulate PAI-1 expression with the 4G/5G genetic polymorphism in kidney cells under hyperosmotic stress. Addressing these issues will contribute to the search for methods to modulate the profibrotic activity of PAI-1 in kidney cells depending on the 4G/5G polymorphism. popup.description2 The aim of this project is to identify signaling pathways and determine the role of transcription factors that regulate PAI-1 expression with the 4G/5G genetic polymorphism in kidney cells under hyperosmotic stress. Addressing these issues will contribute to the search for methods to modulate the profibrotic activity of PAI-1 in kidney cells depending on the 4G/5G polymorphism. Product Description popup.authors Yevhenii P. Kucheriavyi Stohnii Yevhen M. Bilous Vasil L. popup.nrat_date 2025-12-25 Close