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Information × Registration Number 0225U005125, (0124U002194) , R & D reports Title A two-vector method of research and optimization of approaches in the diagnosis and therapy of traumatic conditions of the skeletal muscles of the limbs. popup.stage_title Апробація та оптимізація способів оцінки функціонального стану скелетних м'язів за патологічних станів травматичного генезу та їх терапії. Head Zavodovskyi Danylo O., Кандидат біологічних наук Registration Date 25-12-2025 Organization Bogomolets Institute of Physiology of the National Academy of Sciences of Ukraine popup.description1 The purpose of the project is the development and experimental testing of a combined method of researching traumatic conditions of the skeletal muscles of the limbs, analysis and comparison of the effectiveness of therapeutic approaches, on animal model objects at the first stage of evaluation, by combining tensometry with recording of EMG and M-responses, and at the second stage the proposed experimental design of testing on a robotic research system for the implementation of imposed movement programs will allow to evaluate pathological conditions and their dynamics by means of functional diagnosis of the upper limbs based on the change of marker features of the temporal structure of EMG signals during the execution of movement commands in involved people with orthopedic and/or neuropathological problems at various stages of their treatment. popup.description2 Methods for assessing the functional state of muscles under pathologies of traumatic genesis were optimized in models of post-amputation disuse atrophy and ischemia using automated mechanogram analysis and linear mixed models (LMM), which allowed identifying specific patterns of pathological fatigue and the protective efficacy of a benzo-fused azaheterocycle – Compound Q. Adaptive protocols for a mechatronic device were developed based on the established critical influence of force direction on the formation of electromyogram hysteresis patterns in humans, which serves as an important marker for the diagnosis of post-traumatic disorders. Product Description popup.authors Danylo O. Zavodovskyi Oleksii V. Lehedza popup.nrat_date 2025-12-25 Close