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Information × Registration Number 0226U000811, (0125U001123) , R & D reports Title Development of modern methods for researching injuries and diseases in the war and post-war period popup.stage_title Розробка сучасних методів дослідження ушкоджень і захворювань у воєнний та повоєнний період (І етап) Head Veselovskyi Mykola S., д.б.н. Registration Date 16-01-2026 Organization Bogomolets Institute of Physiology of the National Academy of Sciences of Ukraine popup.description1 The overall goal of the project will be to explore new therapeutic approaches for the treatment of various diseases and injuries, including spinal cord injuries, psychiatric disorders, pathological pain, cancer, cardiovascular diseases, the effects of stress, hyperglycemia, tourniquet syndrome, mine and blast injuries, and burn injuries. It is planned to develop effective methods of diagnosis, prevention, and treatment to improve the quality of life of patients and reduce mortality from these diseases. popup.description2 The developed experimental model of posttraumatic stress disorder (PTSD) in rats using the method of single long-term stress (STS) showed: animals demonstrated an increased level of anxiety, and histological analysis of hippocampal slices revealed significant structural changes in its various zones. The use of endogenous antioxidant glutathione in conditions of systemic inflammation and oxidative stress can significantly improve redox homeostasis, prevent and reduce oxidative stress. When modeling moderate thermal injury, significant histomorphometric changes were found in the liver and lungs, indicating a decrease in their functioning and regenerative properties. The results obtained can be used to determine the inflammatory reaction and severity of pathological processes after thermal injury, as well as to assess the feasibility of surgical intervention. A method of experimental hypoxic therapeutic correction was developed, which had beneficial effects on wound healing and improved regenerative processes in tissues and the blood system in rats with different initial levels of oxygen consumption. Product Description popup.authors Halyna H. Skybo Yaroslav М. Shuba Mariia S. Shypshyna Viacheslav B. Kulyk Ihor В. Philіppov Ірина Г. Літовка Anna-Malgozhata B. Kotliarova Roman V. Yanko Serhii V. Romanenko Mykhaylo І. Levashov Yuliia P. Korkach Nataliia H. Hrushka Anzhela M. Shysh Oleksandr I. Kostiukov Mykola S. Veselovskyi Ruslan B. Strutinskii Tetiana Y. Voznesenska Nataliia M. Rozumna Danylo O. Zavodovskyi Andrii V. Dromaretskyi Alla G. Portnychenko Volodymyr I. Portnichenko Petro K. Tsapenko Ilona I. Chentsova Anna V. Sotkis Victor G. Naydenov Oleksandr M. Bakunovskyi Olena V. Kolosova Nataliia M. Vashchenko Vitalii Y. Maslov Ihor M. Prudnikov Maryna I. Vasylenko Olegh O. Kryshtal Olena A. Kotyk Andriy V. Gorkovenko Oleksii V. Lehedza Olena Lukyanets Vasyl А. Horbachenko Olha I. Kostiuk Nataliia A. Strutynska Lidiia A. Mys Semen I. Yeliashov Mariia H. Kozlovska Vita V. Hanzha Mar yana P. Burlak Oleh V. Halaidych Yevheniya M. Kuliyeva Petro P. Mayorenko Iryna Y. Okhai Kateryna H. Smozhanyk Danylo I. Kravchuk Yuliia O. Bubnova Mykola O. Zavhorodnyi Liudmyla V. Bulgakova Ivan O. Blashchak Аlina P. Lytvynenko Nataliia M. Nevmerzhytska Oleh R. Mezhenskyi Vadym F. Sahach Yulia V. Hoshovska Andrii О. Cherninskyi Serhii O. Shchepanskyi Dmytro I. Shushuiev Kostiantyn V. Koroid Volodymer V. Olianin popup.nrat_date 2026-01-16 Close