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Information × Registration Number 0299U001930, 0197U018429 , R & D reports Title To research the neurobiological mechanisms of effects of trans- and xenoimplantation of embryonic brainspecific tissues, to development the methods of treatment under alcoholism and addiction, affective pathology and limbencephalitis, to approbate them in clinic and to applicate into the practice. popup.stage_title Head Vorobjova T. M., Mynko O. I., Registration Date 30-05-2000 Organization Ukrainian SRI of Clinical and Experimental Neurology and Psychiatry popup.description2 The research was conducted in 436 rats and 303 patients. Objective - the elucidation of mechanisms of the influence of allo- and xenoimplantation of embryonic brainspecific tissues under the modeling of different CNS disfunctions, the development of optimum mode of their usage, the approbation in clinic and application. Methods - neurobehavioural, neurophysiological, electrophysiological, biochemical, immunological, morphological, clinical, psychopathological, mathematical. The neurobiological mechanisms of corrective influence of intracerebral and distant allo-transplantation upon integrative brain activity (orientative-investigative reactions, emotions and memory), motor activity and systemic hemodynamics has been established by using the models of disturbances of psychonervous activity. It has been shown the therapeutic effect of xenoimplantation of embryonic nervous tissues and prolongation of pathogenetic pharmacotherapy under demyelinizing diseases, encephalitis, depressions, alcoholism. Product Description popup.authors popup.nrat_date 2020-04-03 Close