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Information × Registration Number 0299U001941, 0197U018397 , R & D reports Title Researching of influence of phosphatodilholin liposomes for lipids peroxidation in miocard at syndrome of long crashing on subcell level. popup.stage_title Head Yel's'kyj Viktor Mykolajovych, Registration Date 14-05-2001 Organization State Medical University named after M. Gorky popup.description2 Object of research: 180 white nonlinear puberty rats of both sexes of a floor of weight 190-230г., taking place on standard food ration. The purpose of work is to establish character of influence phospholipidis on processes peroxide oxidation lipids in miocard. To give a theoretical substantiation of expediency of using phosphatodilholin liposomes for correction of infringements of lipids peroxidation and decrease of mortality at syndrome of long crushing. Methods of research: are spectrophotometria, fluorimetria, electronic and light microscopia The received results: the efficiency of use phospholipidis for correction of structurally functional damages miocard is proved at syndrome of long crashing Novelty: is established, that the introduction of phosphatodilholin liposomes at syndrome of long crushing results in decrease of the contents of products peroxide oxidation of lipids and increase of antioxidation activity of miocard. The decrease of a degree distruction off cells and subcells membranes allows to support electrical stability of miocard, that allows to recommend clinical approbation of using phospholipidis in complex therapy of traumatic illness. It is introduced: In scientific laboratories DSRIT, CSRL, DSMU in educational process on faculties patophisiology of Donetsk, Zaporozje, Lugansk, Kharkov medical universities. Can be introduced: In laboratories patophisiology and pharmacology of high educational Schools and SRI, using in clinic phosphatodilholin liposomes in complex therapy traumatic a shock. Efficiency: reduction of mortsliyi traumatic illness on 83 % Shock, stress, miocard, phospholipidis, ionol Product Description popup.authors popup.nrat_date 2020-04-02 Close