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Information × Registration Number 0299U004089, 0199U002236 , R & D reports Title Regulatorilly metabolic basis of radiation and cytostatic injuries mechanisms in connective tissue from cancer patients, individual prognosis and correctiveness. popup.stage_title Head Frenkel' L.A., Registration Date 14-12-1999 Organization Grigor'ev Institut for Medical Radiology popup.description2 Aim . To improve the efficacy of antitumor therapy in cancer patient by defining individual prognosis and pharmacological correctives of radiation and cytostatic injuries in connective tissue based on investigation of regulatory and metabolic mechanisms of its development. Methods. Clinical, morphological, hematological, ultra structurally (ultramicroscopic), biophysical, biochemical, statistical. Results. Based on experimental model of total and local exposure and on investigahion of cancer patient the peculiarities of pathological mechanisms of radiation injuries in different kind (pulmonary, liver, intestine, skin, bone marrow) of connective tissue were determinate. For medical treatment (or correctives) of radiation-induced lesions in connective tissue the new drugs Complimin, Lioliv and Altan were used. This drugs were significantly increased the radioresistence of connective tissue and homeostasis's systems. New. The possibilities of individual prognosis and pharmacological correctives o f radiation - induced injuries of connective tissne were assessed Application. Medicine, medical radiology, oncology. Product Description popup.authors popup.nrat_date 2020-04-03 Close