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Information × Registration Number 0300U000261, 0198U001756 , R & D reports Title To develop medico-engineering technology of мechano- chemical modification of biologically active substances for their use in cancer patients. popup.stage_title Вивчені особливості впливу введення механохімічно модифікованих протипухлинних антибіотиків в схемах поліхіміотерапії при комбінованому лікуванні хворих на злоякісні лімфоми, рак ободової кишки та молочної залози. Head Orel V. E., Registration Date 22-02-2000 Organization Ukrainian Research Institute of Oncology and Radiology popup.description2 The object of study: Doxorubicin (DR) after mechanochemical modification (MM), rats with Guerin's carcinoma, patients with colonic, breast cancers and malignant lymphomas. The objective: The development of technology MM DR for use in polychemotherapy (PCT) of oncologic patients. Methods of examination - clinical, physico-chemical, statistical. Instruments: micromill MMVE-0,005, diphractometr DRON-2.0, spectrometr SPECORD M40, IR-spectrometr UR-20, spectrofluorimetr SDL-2. MM DR technology has been developed. The improvement of the immediate results of PCT and decrease of side effects (leukopenia, erythropenia, ECA changes). Field of application - oncologic institutions. Product Description popup.authors popup.nrat_date 2020-04-03 Close