Search academic texts

Information × Registration Number 0301U000322, 0198U007235 , R & D reports Title Chiral sulfoxide controlled asymmetric additions to C-N double bond. An effcient approach to stereochemically defined a-fluoroalkyl amino compounds popup.stage_title Асиметричне приєднання монохіральних фторованих сульфоксидів до фторомісних імінія, як метод синтезу енантіомерно чистих біологічно активних фторамінокислот Head Sorochyns'kyj O.Ye., Registration Date 09-02-2001 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 The asymmetric addition reaction between a-lithium derivatives of enantiomerically pure methyl and benzyl p-tolyl sulfoxides and N-(p-methoxyphenyl)aldimines found to proceed under mild conditions allowing for convenient preparation of a-fluoroalkyl B-sulfinylamines in excellent yieds and good enantiometric purity. The stereochemical outcomes of these reactions were shown to be subject to cinetic control, that is in starp contrast to the corresponding reactions. Product Description popup.authors popup.nrat_date 2020-04-02 Close