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Information × Registration Number 0302U005123, 0100U003382 , R & D reports Title To determinate mineral and organic phases structure changes and rebuildingof DNA in development of radioinduced oncohaematologycal pathology аnd allied deseases of victims by Chernobyl accident in distant period popup.stage_title Оцінити склад мінеральної та органічної фаз кісткової тканини у постраждалих з радіоіндукованими лейкеміями і спорідненими захворюваннями у віддалений період після аварії на ЧАЕС Head Bebeshko Volodymyr Grygorovych, Доктор медичних наук Registration Date 01-03-2002 Organization Research Centre for Radiation Medicine popup.description2 Object of investigations: 197 children and adult with leukemias and congenerous diseases of the Chernobyl accident victims. Methods: clinical, biochemical, biophysical, immunological, mathematical. The purpose: study structure of mineral and organic phases of an bone at the injureds with leukemias and congenerous diseases in the remote term after failure. At the patients with ALL the contents dihydrophosphate calcium in urine is higher, than in bunch of comparison. At children with acute myeloblastic leukemias the contents of phosphas calcium in urine is higher, than at the patients with ALL. Decreased of the basic forms of calcium phosphates of a mineral component at liquidators, rising of the contribution of an organic component of firm tissues of dens in comparison with mineral. The rising asparagine and glutamate aminoacids in serum of a blood is revealed. The sum free aminoacids at the patients by a leukemias below physiological on 29 %. Increased hydrophobic of a molecula of a collagen of a b one in the developed phase of a leukemia. The changes as an osteoporosis, destruction in bones are revealed. Density of bones at the majority of children was below age on 35-50 of %. Product Description popup.authors popup.nrat_date 2020-04-02 Close