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Information × Registration Number 0302U005166, 0100U003316 , R & D reports Title Investigates of regulation proliferation mechanisms for adaptation progress to action of the heavy metals in animaland plant cells during different phases of ontogenesis. popup.stage_title Дослідити механізми екскреції іонів міді із клітин тварин та рослин та підібрати речовини , які посилюють швидкість виведення важких металів з організму молодих та старих тварин. Head Bozhkov A.I., Registration Date 25-03-2002 Organization Kharkov National University named after V.N.Karazin popup.description2 Object of investigation - cjpper ions, collagen, mitochondria.Purpose of study -investigating excretion mechanism of the cupper ions from animal cells and plants and selection substance, which to reinforce excretion rate of the heavy metals from organism of young and old animals.At experiment it has been used 35 rats-male 5-8 months age. During experiment we determined of animal mass and evaluated detoxication function of liver. At the blood serum we determined of the general lipids content. Intoxication of the experimental animals by the repeated injections of the copper sulfate made worse physiological status of animals and leaded to decrease of mass and pathological changes. Pathological changes in animals, which did not receive of beer, its have been expressed much less. The copper ions accumulated in mitochondria and leaded to decrease of functional activity these organells. Adaptationprocesses in rats of the different age are directed on improvement of the mechanical capacity of connective tissue. Product Description popup.authors popup.nrat_date 2020-04-02 Close