Search academic texts

Information × Registration Number 0302U005167, 0100U003323 , R & D reports Title Role of heme and hemoproteins in regulation of metabolic adaptation systems under oxidative stress. popup.stage_title Вивчити дію солей важких металів, іони яких не здатні включатись в протопорфіринове кільце, на метаболізм гему і ліпідів печінки та вміст гемопротеїнів і ліпопротеїнів сироватки крові тварин. Head Kaliman P.A., Registration Date 25-03-2002 Organization Kharkov National University named after V.N.Karazin popup.description2 The aim of this study was to investigate the role of heme and hemoproteins in the regulation of adaptation systems under the oxidative stress, The heme oxygenase, tryptophan -2,3 -dioxygenase , delta - aminolevulinic acid synthase, superoxyd dismutas, catalase activities, cytochrome P-450 content and the level of spontancous and ascorbat -induced LPO in liver of rats and absorbtion spectrum blood serum in Soret region and in 280 nm at different times after CdCl2 administration and a -tocopherol and CdCl2 co- administration was studied.The Wistar rats were used in the work. Mechanism of oxidative stress progress in the liver is the accumulation of the hemolysis products content in blood serum and their entering in this organ. Co-administration of a - tocopherol and CdCl2 doesn't prevented the oxidative stress caused by cadmium chlorid in rat liver. Product Description popup.authors popup.nrat_date 2020-04-02 Close