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Information × Registration Number 0302U007445, 0100U006465 , R & D reports Title The investigation of the epilepsy resistant forms development on the experimental status epilepticus and postkindling in different ages rats with the aim of their cessation pharmacological treatment performing out. popup.stage_title Вивчити ефекти карбамазепіну, вальпроату та фенобарбіталу, а також препаратів-блокаторів кальцієвих рецепторів за умов післякілдлінгу у щурів різного віку. Head Shandra Alexey Antonovich, Registration Date 25-12-2002 Organization Odessa state medical university popup.description2 The different effects of the classical antiepileptics - carbamazepin, valproic acid and phenobarbital - in rats in picrotoxin kindling and postkindling models. The antiseizure effects of valproic acid and phenobarbital were decreased during postkindling. The carbamazepin efficacy preserves but in the maximal dose. The named drugs antiepileptic efficacy failed to be performed in the pups. The data obtained are the exprimental background for the pharcological resistency phenomenon formation throughout the chronic forms of the epileptic activity. Product Description popup.authors popup.nrat_date 2020-04-03 Close