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Information × Registration Number 0303U001409, 0101U000886 , R & D reports Title To develop medical-engineering technology for use activated doxorubicin and electromagnetic irradiation on the tumor popup.stage_title Вплив комбінованої дії механохімічно активованого препарату та електромагнітного випромінювання на культуру пухлинних клітин. Head Оrel V. E., Registration Date 28-02-2003 Organization Ukrainian Research Institute of Oncology and Radiology popup.description2 The object of study- doxorubicin, carcinoma Guerin; tumor cells of man : carcinoma of mammary gland MCF-7; T-cells of acute lymphoblastic leukemia MT-4, adenocarcinoma of lungs A-549. The aim - development of physics-technical basis for medical-engineering technology during combination using for mechanochemical activated drug , electromagnetic irradiation and study their influence on experimental cancer process. Methods of study - physical-chemicals and statistics. Equipments- mechanochemical modifier MMVE-0,005; mechanoemission analyzer ТРА-3; the apparatus "Luch-3 SMV-20-3", the apparatus VHF; the apparatus "Oratorya"; the ultrathermostat "Type 03";the thermostat TS-80M-2; flowing cytofluorimetr FACScan. The construction , appendix to MTV developed and manufactured experimental apparatus for irradiation in VHF-diapason of culture cells and laboratory animals. Combination mechanochemical activated doxorubicin and electromagnetic irradiation VHF-, UHF-, EHF-diapasons decreased of volume carcinomaGuerin on average 44% in comparison with experiments with officinal antibiotics. VHF-irradiation produced moderate hyperthermia effect with big penetrate into biological tissue. Combination mechanochemical activated doxorubicin and electromagnetic irradiation VHF-diapason at 370C on culture cells MCF-7,MT-4 and A-549 produced of the tendency to increase anticancer effects in comparison with experiments with officinal antibiotics. Product Description popup.authors popup.nrat_date 2020-04-02 Close