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Information × Registration Number 0303U007898, 0100U000591 , R & D reports Title Study of glycoconjugates as biochemical markers of pathology popup.stage_title Вивчення ступеню та характеру глікозильованості клітинних та позаклітинних білків, гуморальних факторів імунологічного захисту при патологычних станах. Head Brazaluk A.Z., Registration Date 25-12-2003 Organization Dniepropetrovsk State Medical Academy popup.description2 We were investigated the glycosylation of IgG and formation of complexes IgG- fibronectin in the norm and at some pathological conditions (preeclampsia, cancer and system sclerodermia). It is established that the structure of carbohydrate component of IgG in retroplacental blood of the pregnant woman with preeclampsia differs from the glycane of mother IgG. Quantity of IgG-bounded fibronectin (IgG-FN) in mathernal serum is sharply reduced at high-gravity preeclampsia, inverse tendency has this ratio for the fetus. At a preeclampsia , cancer and system sclerodermia FN in IgG-FN complexes is degraded, the degree of its degradation depends on type and gravity of pathology. Product Description popup.authors popup.nrat_date 2020-04-02 Close