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Information × Registration Number 0304U001599, 0102U005682 , R & D reports Title Study of prenatal irradiation remote effects in children with gestation age and organs & tissues dose values takinginto account. popup.stage_title Продовження комплексного обстеження підлітків, які зазнали внутрішньоутробного опромінення та визначення особливостей функціонування органів і систем в постнатальному онтогенезі в залежності від гестаційного віку та дози опромінення плода Head Stepanova Eugenia Ivanovna, Доктор медичних наук Registration Date 10-03-2004 Organization Research Centre for Radiation Medicine popup.description2 Object of the study: Children exposed to radiation in uterо. Aim of the study: To investigate the adolescents irradiated in the term of the intrauterine development in distant periods after the Chernobyl accident on the basis of the results of complex clinical-laboratory examination. The peculiarities of functioning organs and systems in postnatal term of oncogenesis depending on gestation age and dose of fetal radiation were determined. Dyshormonic type of the physical development was more frequently noted in children irradiated in the early terms. The phatological formation of puberty and the increase in the thyroid size were revealed from 9 to 16 weeks of the intrauterine development. An improvement of the functioning surfactant respiratory system, the decrease in intensity of free radical processes in organism biomedium were observed. The presence of dissatisfied adaptation of the cardiovascular system against the environmental conditions is caused by dyscoordinated changes in the indices of operative regulation in the cardiac rhythm. Maximal rate of deformity of the gall-bladder, the hernia and the oesophageal diaphragm opening are registered in children irradiated before the 8 week of gestation that explains the abnormal processes of embryogenesis. Ultrastructural changes in membranes and different disorders in structure of intracellular organelles are registered, the stable disorders in chromosome apparatus are prevailed but their frequency was significantly decreased comparing to the previous period. Product Description popup.authors popup.nrat_date 2020-04-02 Close