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Information × Registration Number 0304U002244, 0101U002485 , R & D reports Title The role of non-cholinergic factors (histamine, motiline and endothelial factors) in the regulation of functional state of gastrointestinal tract popup.stage_title Дослідження участі NO-синтази у регуляції кровообігу і дихання печінки Head Beregova Tetyana Volodimirovna, Registration Date 27-02-2004 Organization Taras Shevchenko Kiev university popup.description2 It was established that AH and L-arginin stimulate tissue oxygenation in the liver and decrease the level of oxygen in it through the action of NO-synthetase. On the dogs with intact nervous system motilin receptor agonists inhibit gastric secretion stimulated by carbachol, histamine and penthagastrin but doesn't influence on insulin secretion. Unselective blockator of NO-synthetase L-NAME abolishes macrolid inhibitory action on histamine gastric acid secretion. It is the evidence that macrolids initiate the realizing of NO from inhibitory interneurons of enteral nerves system thought excitation of motilin receptors. Development of gastric ulcer accompanies by structure reorganization of gastric mucosal membranes that can leads to modifications of transport and intracellular regulatory systems5635 Product Description popup.authors popup.nrat_date 2020-04-02 Close