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Information × Registration Number 0304U002775, 0102U006588 , R & D reports Title Molecular-genetic and ecologic dependent mechanisms of reproductive system neoplasms developing: ways of diagnostics improving, treatment and prophylaxis popup.stage_title Визначити основні молекулярно-генетичні екозалежні механізми етіології та патогенезу пухлин репродуктивної системи. Head Zaporozhan Valery Nikolaevich, Registration Date 20-12-2004 Organization Odessa state medical university popup.description2 It has been established molecular and genetic mechanisms of endometrial hyperplasia, uterus myoma, endometrial and breast cancer. We have observed the role of NAT2 gene in pathogenesis of uterus myoma and endometrial carcinoma. We've detected high frequency of spontaneous chromosome instability in patients with uterus myoma, the presense of extra-marker chromosomes, absense of some chromosomes, in patients with endometrial cancer. It has been established higher degree of transcription cofactor TIF2 and progesterone receptor-beta expression in uterus myoma, than in breast cancer cell line MCF7. Product Description popup.authors popup.nrat_date 2020-04-02 Close