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Information × Registration Number 0304U004453, 0103U007748 , R & D reports Title Role of polyamines in transcriptional regulation of genes involved in neoplastic growth popup.stage_title Дослідження впливу поліамінів на активацію фактору транскрипції NF-kappaB з використанням спектрометра поверхневого плазмонного резонансу Head Chekhun Vasyl Fedorovich, Registration Date 02-07-2004 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 Using computer modeling methods, the search for potential polyamines-binding sites on the nuclear transcription factor NF-kappaB was performed. It is shown that the presence of polyamines in the revealed site facilitates formation of NF-kappaB - DNA complex. A method for protein immobilization on the surface plasmon resonance sensor chips was developed. In vitro studies of polyamines influence on the functional activity of NF-kappaB were performed. Product Description popup.authors popup.nrat_date 2020-04-02 Close