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Information × Registration Number 0305U003155, 0103U001408 , R & D reports Title To determine a role of blood genetic systems and some molecular-genetic markers of tumoral clones in a complex estimation of efficiency of a transplantation stem hemopoietic cells at patients leukemias, lymphomas and solid tumours popup.stage_title Вивчення фенотипової асоційованості маркерів різних генетичних систем крові, цитогенетичних і молекулярно-генетичних порушень з особливостями перебігу захворювання на різних етапах трансплантації кісткового мозку та стовбурових клітин периферичної крові. Head Bebeshko Vladimir, Доктор медичних наук Registration Date 23-02-2005 Organization Research Centre for Radiation Medicine popup.description2 Object: children and adults with leukemias, lymphomas and solid tumours. The purpose: to estimate clinical current oncologic and oncohaematologic pathologies in interrelation with immunogenetic structure and a spectrum of molecular-genetic markers at patients - candidates for realization of a transplantation hemopoietic stem cells and recipients of a transplant. Methods: clinical, hematological, immunogenetic, immunological, cytogenetic and molecular-genetic. Features of current and results of treatment of 75 patients with oncohaematological pathology were analysed. It fixed, that current of oncologic diseases at the investigated contingent with presence of the certain clinical attributes is in interrelation with immunogenetic markers of a blood, has the diseases of association appropriate to the form with concrete genotypical characteristics of HLA-system. Molecular-genetic, cytogenetic and immunogenetic diagnostics of oncohaematological diseases promoted definition of strategy of therapy and an individualization of treatment, definition of expediency of a transplantation as to therapy of a choice and optimum term of its realization,prediction for minimization of aftertransplantation complications. Product Description popup.authors popup.nrat_date 2020-04-02 Close