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Registration Number

0306U008444, 0103U007872 , R & D reports

Title

The peculiarities of course of ulcerative colitis in Donetsk industrial region

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Особливості перебігу неспецифічного виразкового коліту у Донецькому промисловому регіоні

Head

Berezov V.M.,

Registration Date

22-11-2006

Organization

Donetsk state medical University named after M. Gorky

Description

OBJECT: 180 patients with different forms of ulcerative colitis (UC) were examined. Among them were 89 (49,4%) men and 91 (50,6%) women in age from 17 to 65 years. 150 patients with the irritable bowel syndrome at the same age were examined as a control group. All patients lived in the Donetsk industrial region. AIM OF STUDY: increasing of diagnostic quality of different forms of UC in patients resident in the Donetsk industrial region. NOVELTY: Frequency of different forms of UC in the Donetsk industrial region was studied, the role of extrabowel manifestations of UC, risk factors of their origin, in patients with UC from Donetsk region is first appraised, new criteria of diagnostics of extrabowel manifestations of UC were exposed. RESULTS: sex structure and frequency of different forms of UC in industrial Donetsk region were estimated. Clinical, hematological and endoscopical parameters for course, distribution and process acuteness in patient with UC were presented. Predispose and provocative factors of total UC were discovered. Histological changes of slim were studied. Frequency and clinical features of extrabowel manifestations of UC were evaluated. EFFICIENCY: to provide more earlier diagnostic of UC, to decrease time period to establish final diagnosis, give the possibility for timely treatment administation of UC, to reduce quantity of severe forms of UC, decrease frequency of invalidisation, improve quality of life in these patients.

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