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Information × Registration Number 0306U008455, 0103U007889 , R & D reports Title Regularities of destructive lung tuberculosis forming during epidemy period (pathogenesis, clinic, diagnoses, prophylaxis, treatment) popup.stage_title Закономірності формування деструктивного туберкульозу легень у період епідемії (патогенез, клініка, діагностика, профілактика, лікування) Head Korzh Elena V., Registration Date 22-11-2006 Organization Donetsk state medical University named after M. Gorky popup.description2 Object of investigation: 205 patients with destructive lung tuberculosis, 25 healthy people, 15 healthy medical collaborators of tuberculosis hospital, 250 case histories. Purpose of work: to find the main regularities of destructive lung tuberculosis forming during epidemic period in industrial Donetsk region with analyses of organism staying and pathomorphological changes, to develop the methods of damage correction. Methods of investigation: hygienic, clinical, laboratorial, biochemical, immunological, morphological, statistical. The obtained results and newness: it was found that the development of destructive tuberculosis is a result of decreasing of cells immunity, that promote of damage of micro vessels in the lung and increase of capacity of tissue injure. The formation of fibrin-caseose blob and lisys of fibrin mass promote the destructive emergence. The criteria's of immunity correction were founded. Inclusion rasthoropsha pyatnistaya in complex therapy of tuberculosis improvs the processes of healing and preventions of development of by-effects on antitubercular drugs. Product Description popup.authors popup.nrat_date 2020-04-02 Close