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Information × Registration Number 0307U001690, 0106U001579 , R & D reports Title Investigate cell, genetic mechanisms of age changes and adaptability popup.stage_title Вивчити вплив генотипу на перебіг онтогенезу та прояви адаптивно важливих ознак організмів Head Shkorbatov U.G., Registration Date 19-04-2007 Organization Kharkov national university named after V.N. Karazin popup.description2 Report about Scientific Technique Work: 72 p., 20 fig., 13 tables, 88 literature cites The Objects of the studies: lines and interline hybrids of drosophila, politene chromosomes of the salivary glands of drosophila, seeds of agricultural plants, cells of human buccal epithelium. Purpose of the study: fundamental experimental study on cellular and organism level of such important problems as age-related genetic mechanisms to adaptability and their interactions in different model object Methods of the study: study of chromosome politenia degree in drosophila, chromosome aberrations assessment, study of mitotic cycle dynamics and other cytological characteristics, studies of gene expression, registration of the electrokinetic characteristics of cell nucteus, study of the chromatin state in human cells. Results of the study: Are sown results of the studies which concern genetic and cytological mechanisms of stress reaction of cells and organisms on physical and chemical factors action, in particular ionizing and electromagnetic irradiation effects, effects of hormones and hormone like substances, cell effect of changes in condition of with age and fatigue. The regularities in radio adaptive answer of plant cells of the plants in connection with heterosis effect are shown. The effects of the stress provoked by chemical factors in particular hormones and hormone like substances, and some alkaloids on gene activity, degree of politenia in drosophila politene chromosomes, and on frequency of dominant lethal mutations, are also shown. The influence of the cultivation conditions and age of the parents on viability and fecundity of drosophila are demonstrated. Changes in chromatin condition in human cells under the influence of electromagnetic fields, fatigue and donor's age are shown. Product Description popup.authors popup.nrat_date 2020-04-02 Close