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Information × Registration Number 0307U001768, 0105U001316 , R & D reports Title Investigation of vitamines B 1, B 6 derivatives influence on mammals neuromuscular transmission popup.stage_title Дослідження впливу похідних вітамінів В 1, В 6 на нервово-м'язову передачу у ссавців Head Romanenko Olexander, Registration Date 26-04-2007 Organization National Medical University popup.description2 Vitamine B 1 antagonists oxythiamine and perithiamine provoke decrease of amplitude and quantal content of end-plate potentials (EPP), perithiamine provokes also decrease of amplitude of miniatyre EPP in the mice diaphragm synapse. Differens in the parameters of inhibitory synaptic potentials (ISP) in human small intestine and colon and quines pig colon smooth muscles were found. Among endogenous vitamine B 6 forms namely pyridoxol-5' -phosphate provokes effective ISP latent period increase and ISP amplityde decrease and also adenosinetriphosphate evoked smooth muscle cells hyperpolarization decrease. Product Description popup.authors popup.nrat_date 2020-04-02 Close