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Information × Registration Number 0307U003542, 0104U009150 , R & D reports Title Stydy of the factors influencing the yield and stereoselectivity in glycosylation of anthracycline aglycones popup.stage_title Вивчення факторів, що впливають на вихід і стереоселективність реакції гликозилювання антрациклінових агліконів Head Matvienko V.N., Registration Date 04-04-2007 Organization The L.M.Litvinenko Institute of Physical-Organic Chemistry and Coal Chemistry popup.description2 The work was carried out along the following lines: development of the procedure of 7-Hal-rubomycinone synthesis; studies on the factors influencing the yield and stereoselectivity of 7-Hal-rubomycinone reaction with activated hydroxyl-containing glycosides; measurements of the catalytic activity of transition metals in hydroxylation of activated anthracycline aglycons. The optimum conditions of the rubomycinone and 7-Hal-rubomycinone syntheses have been developed; structure and medium effects of the glycosidation components on the reaction yield and stereoselectivity have been studied. Product Description popup.authors popup.nrat_date 2020-04-02 Close