Search academic texts

Registration Number

0308U001121, 0106U002360 , R & D reports

Title

To create the methodology of bronchopulmonary system clinical monitory of persons from the high risk of oncological pulmonary diseases in conditions of radionuclides influence of emergency and natural origin

popup.stage_title

Сформувати групи ризику розвитку онкопульмонологічних захворювань з осіб, які зазнають впливу радіонуклідів аварійного аварійного та природного походження. Провести комплексне пульнологічне дослідження стану бронхолегеневої системи осіб, які зазнають інгаляційного впливу радіонуклідів аварійного та природного походження

Head

Sushko V.A.,

Registration Date

21-01-2008

Organization

Research Centre for Radiation Medicine

popup.description2

Object: retrospective estimation of lung cancer cases in the clean up workers of Chernobyl NPP accident, bronchopulmonary system of people, who underwent to radionucleads inhalation (pulmonology screening) (n = 102), bronchopulmonary system of the participants of liquidation of Chernobyl Catastrophe consequences (n=30), Object "Shelter" workers (n=28). Purpose of work: to provide the prospective study of clean up workers of Chernobyl NPP accident, inhabitants of the territories with high indoor radon 222 level, Object "Shelter" personnel for the estimation of oncopulmonary pathology risk factors. Methods: clinical, functional, X ray, endoscopy, immunological, screening (pulmonary screening), statistical. Case control study of 275 Chernobyl NPP accident clean up workers showed the tendency to dose relation of oncological pulmonary pathology in irradiation for 0,25 Gy in the conditions of possible radionucleades inhalation. The results of pulmonology screening and complex investigation showed the importance of clinical epidemiological study for the development of oncopulmonary pathology in those, who underwent to radionucleades inhalation of emergency and natural origin. The differences in activation status of alveolar macrophages and spectrum of cytokines were found. The formation of risk group for oncological pathology was started for the future prospective study. The oncology marker panel was created for the early diagnosis of lung cancer in those, who underwent to radionucleades inhalation.

Product Description

popup.authors

popup.nrat_date

2020-04-02