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Information × Registration Number 0308U003106, 0106U000960 , R & D reports Title Searching of epidemiology and specifities of immunopathogeneses of latent syphilis, propose methods of its treatment popup.stage_title Вивчення особливостей імунопатогенезу прихованого сифілісу та розробка діагностичного алгоритму обстеження, обґрунтування методу лікування сифілісу Head Mavrov G.I., Registration Date 04-03-2008 Organization SE "Institute of dermatology and venerology of AMS of Ukraine" popup.description2 For the almost 30 % of cases of latent syphilis slightly positive, controversial and, partly negative serologic tests for syphilis are typical. The new features of the immune answer of patients with the latent syphilis is established: the misbalance of IL-1betta, IL-4, IL - 6, INF-gamma, TNF-alfa is revealed, more expression of, which are produced Тh-1-lymphocytes - IL-1betta, INF-gamma, TNF-alfa takes place. The misbalance of IL-4, IL - 6 was revealed in latent syphilis in comparison with active syphilis. The deviation of the cytokine levels from statistical norm in patients with late syphilis is more pronounced. Product Description popup.authors popup.nrat_date 2020-04-02 Close