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Information × Registration Number 0308U003255, 0106U003123 , R & D reports Title Investigation of mechanisms of epigenetic changes in the process of adaptation in the different age groups of animals popup.stage_title Вплив різноманітних факторів на оборотність епігенетичних змін Head Bozhkov A.I., Registration Date 19-03-2008 Organization Kharkov national university named after V.N. Karazin popup.description2 Object of investigation - epigenetic changes. The investigations were carried out on Wistar rats age 3 and 21 month. The rats were divided on the groups with different diets and dietary habits. The intraperitoneal introduction of CuSO4 in dose 0,23 mg/g of liver were realized in every 48 hours to several groups. Work aim - investigation of reversible of the epigenetic changes under different influences. Methods of research - immunological and biochemical methods: determination of glucose-6-phosphatase activity, content of protein, and the influence the copper ions on. Diets influence on the functional activity of the immune system, but diets, which limit the growth, it don't decries of the ability to the adaptation of young and adult rats to such stress-factors as toxic metals. Product Description popup.authors popup.nrat_date 2020-04-02 Close