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Information × Registration Number 0309U000096, 0108U000193 , R & D reports Title To determine molecular changes in cancer cells of the patients with refractory forms of malignant lymphomas, to define diagnostic and prognostic value of these changes, to develop the methods of treatment depend on levels of these changes. popup.stage_title Вивчення рівня експресії протеїн–кінази с? при різних гістологічних варіантах злоякісних лімфом. Визначення взаємозв’язок між клінічним перебігом захворювання та рівнем експресії протеїн-кінази с? Head Kryachok Iryna, Registration Date 26-01-2009 Organization Ukrainian Research Institute of Oncology and Radiology popup.description2 Object of study – patients with refractory forms of malignant lymphomas. Objective of study – to determine the diagnostic and prognostic value of the molecular changes in cancer cells of patients with refractory forms of malignant lymphomas and to develop the methods of treatment depending on levels of these changes. Methods of study – clinical, hematological, morphological, imunohistochemical, radiological, statistical. To asses not only clinical, but also immunohistochemical prognostic markers of the disease while primary diagnoses and to assign the group of primary refractive patients. This group need more aggressive scheme of polychemiotherapy in the first line of treatment to achieve a complete response. Field of use – oncology.5635 Product Description popup.authors popup.nrat_date 2020-04-02 Close