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Information × Registration Number 0309U000872, 0108U001540 , R & D reports Title Stratification of patients with high level of development of cardiovascular complications on the basis of the detailed analysis of proteolytic processes in connectivetissue. popup.stage_title Дослідження активності металопротеїназ у хворих з інфарктом міокарду Head Dzyak Georgy Victorovich, Registration Date 04-01-2010 Organization Dniepropetrovsk State Medical Akademy popup.description2 108 patients have been examined. They were divided by clinical characteristic into 4 groups: 1 - QMI with the elevation of ST and TLT; 2 - QMI with the elevation of ST without TLT; 3 - non QMI; 4 - with post-infarction cardiosclerosis. It was established qualitative and quantitative changes of fibronectin that reflected features of clinical course of the disease. It was proved that ratio of activity levels of MMP-2/MMP-9 had greater diagnostic value than determination of distinct gelatinases. It had been shown that among patients predominated gomozygotes C-C of promotive zone - 1306 MMP-2 gene and 15662 MMP-9 gene. It had been determined 2 cases of pathological variant of MMP-2 gene which did not correlate with clinical course of the disease. Product Description popup.authors Іванов А.П. Бразалук О.З. Дзяк Г.В. Каплан П.О. Коваль О.А. Мараренко О.А. Пелешенко Г.Б. Сенюк В.Ф. Стєклєньова Н.І. Шаульська О.Е. Шевцова А.І. Штепа О.В. popup.nrat_date 2020-04-02 Close