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Information × Registration Number 0309U003332, 0108U004043 , R & D reports Title Development of a method of management by synthesis of structural biological polymers of a connecting fabric fjr application in surgery and orthopedy popup.stage_title Розробка методу управління синтезом структурних біополімерів сполучної тканини для використання в хірургії і ортопедії Head Perskiy E., Registration Date 21-04-2009 Organization Kharkov national university named after V.N. Karazin popup.description2 Object of research - synthesis and structure of collagen of type I and biomechanical features of a skin of rats. A research objective - possibility finding-out to regulate intensity synthesis and structurally - molecular features of collagen of type I and biomechanical features дермы skins action of mechanical pressure. Research methods - инкубация worrying bodies, measurement of activity of enzymes to collagen processing, the radio isotope analysis, spectrophotometry, measurement of biomechanical features of a skin. Increase of external mechanical pressure in a skin of rats to 0,18 МН/м2 raises intensity of synthesis of collagen of type I, reduces degree oxidising дезаминивания лизила and hydroxilizil in it and level cross-section covalent sewings together in it overmolecule formations. The quantity connected with collagen гексоз grows that testifies about level increases glycoziling in synthesised molecules of collagen. Thus rigidity of a skin raises, and the size of its not elastic deformation decreases. The general conditions are described, allowing action of external mechanical pressure to regulate intensity of synthesis of collagen of type I in a skin, structural characteristics of its molecules and is viscous-elastic features of this fabric. Product Description popup.authors popup.nrat_date 2020-04-02 Close