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Information × Registration Number 0310U008116, 0106U001416 , R & D reports Title Studying of "structure-activity" relationships in the 1,4-benzdiasepine and 1,2-dihydroquinoline derivatives, their pharmacodinamics, pharmacokinetics, phisics-chemical properties and bioavailability after various methods of administration popup.stage_title Вивчення фармакологічних властивостей похідних 1,4- бенздіазепіну та 1,2-дигідрохіноліну. Head Andronati Sergiy Andreevich, Registration Date 06-12-2010 Organization Odessa I.I.Mechnikov National University, Research Institute "Astronomical Observatory" popup.description2 Was study anticonwulsantactivity of the new 1,2-1,2-dihydro-3H-1,4-benziazepine and 1,2-dihydroquinoline derivatives by corazole test. Was specified the relationship between structure and activity. Was show then investigated material had high anticonvulsant action. We showed that most active lauric and enantic esters of 1,4-benziazepine. The lauric esters are most activity at transdermal delivery, and enantic esters at the oral administration. Product Description popup.authors Александрова О.А. Бойко Ю.О. Грищук Л.В. Кириченко І.М. Кравченко І.А. Радаєва І.М. Сівко Г.І. Турянська Г.М. Федорова О.А. popup.nrat_date 2020-04-02 Close