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Information × Registration Number 0313U005077, 0108U003041 , R & D reports Title Creation and pharmacological scrining of new psychothropic of means. popup.stage_title Створення та фармакологічний скринінг нових психотропних засобів. Head Koreniyk Ivan Ivanovich, Registration Date 14-02-2013 Organization National Taurida V. Vernadsky University popup.description2 It is exposed, that N-acelirovannye of amino acid – (COOH) Ph, Conh-ala, Conh-val and Conh-gly – show protivovospalitel'nuyu activity. Among the tested connections Conh-val has the most expressed protivovospalitel'noe action and on the first minutes of experiment exceeds diklofenak on force. The tested derivatives of amino acid possess a psikhotropnym action which is expressed in the change of povedencheskikh reactions of rats in the experimental models of stress. Connections of SOnh-ala, Conh-val and Conh-gly. When comparing the effect of the nature of carbohydrate residue on psychotropic activity revealed that the highest activity among the investigated derivatives ?-alanine showed glyukozaminid salicylic acid, the effect of which, in most cases, exceed the corresponding p-isomers, and conjugates 2-karboksifenilglyukozida diatsetongalakturonovoy acid. The study matched the conditions of synthesis of amino acid conjugate. Product Description popup.authors Гамма Т.В. Коренюк І.І. Кур'янов В.О. Раваєва М.Ю. Хусаінов Д.Р. Чупахіна Т. popup.nrat_date 2020-04-02 Close
R & D report
Head: Koreniyk Ivan Ivanovich. Creation and pharmacological scrining of new psychothropic of means.. (popup.stage: Створення та фармакологічний скринінг нових психотропних засобів.). National Taurida V. Vernadsky University. № 0313U005077
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Updated: 2026-03-26