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Information × Registration Number 0313U005133, 0108U006381 , R & D reports Title To develop a sustem of measuares and effective prophylaxis way of calves and peglets pneumoenteritis caused by conditional pathogenic bacteria popup.stage_title Розробити і випробувати в виробничих умовах дослідні зразки інактивованої полівалентної вакцини з патогенів, які циркулюють в господарствах Head Rudenko Anatoliy Fedorovich, Registration Date 30-05-2013 Organization Lugansk national agrarian university popup.description2 A report includes 49 pages of text, 15 pictures, 10 tables and 64 literary source. For inactivation of microorganisms which enter in the complement of the vaccine developed by us, the subletales concentrations of suroxide of hydrogen (0,3%) and formaldehyde are used (0,1%). In comparative experiments certainly term of complete inactivation of bacterial mixture of E. coli (O8, O26, O111, O138), P. aeruginosa, K. pneumoniae, S. epidermidis, which takes place through 13,0; 12,9; 12,8; 13,0; 12,7; 12,5; 13,3 hours accordingly. Antigens, for inactivation of which applied the subletales concentrations of suroxide of hydrogen (0,3%) and formaldehyde (0,1%), had a large adjuvanticity and less toxicness, as compared to antigens, for inactivation of which applied the suroxide of hydrogen (0,5%) or formaldehyde (0,3 %). Doklinicheskie tests rotined also, that making of series of inactivation vaccine were sterile and harmless for white mise. A vaccine inactivation against pnevmoenterit piglings, caused de bene esse by a pathogenic microflora which is made from the associations of local stamms de bene esse rotined pathogenic microorganisms (E. coli O8, O26, O111, O138, P. aeruginosa, K. pneumoniae, S. epidermidis) the best preventive properties (76,5 - 89,8%), as compared to a biofactory vaccine (69,8%). Piglings are got from graft sows, had the best defence (89,8%), what piglings which were got from ungraft sows (76,5%). Application of vaccine inactivation, against pnevmoenterit piglings, caused de bene esse by pathogenic microorganisms enables to provide the accumulation of aglutin antibodies in the wheys of blood of piglings within 6 months, that in same queue guarantees reliable defence of graft population against the diseases of gastroenteric, respirator, which are conditioned by an action de bene esse of pathogenic microorganisms. Product Description popup.authors Бабенко Олексій Петрович Заболотна Валентина Павлівна Затуліна Ірина Сергіївна Клименко Сергій Сергійович Ладиженська Катерина Іванівна Руденко Анатолій Федорович Санін Микола Олександрович Тресницька Вероніка Анатолієвна popup.nrat_date 2020-04-02 Close
R & D report
Head: Rudenko Anatoliy Fedorovich. To develop a sustem of measuares and effective prophylaxis way of calves and peglets pneumoenteritis caused by conditional pathogenic bacteria. (popup.stage: Розробити і випробувати в виробничих умовах дослідні зразки інактивованої полівалентної вакцини з патогенів, які циркулюють в господарствах). Lugansk national agrarian university. № 0313U005133
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Updated: 2026-03-22