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Information × Registration Number 0313U005212, 0112U003969 , R & D reports Title Development of approaches and synthesis nitrogen containing bisphosphonates (4-substituted pyrazole derivatives according to the length of linker) popup.stage_title Розробка підходів та синтез нітрогенвмісних бісфосфонатів (4-заміщені похідні піразолу у відповідності до довжини лінкера) Head Volochnyuk Dmytro Mikhalovich, Доктор хімічних наук Registration Date 29-10-2013 Organization Institute of Organic Chemistry National Academy of Sciences of the Ukraine popup.description2 The object of research is the development of preparative methods of synthesis of nitrogen-containing bisphosphonates. The studies produced results that encourage the development of drugs against osteoporosis, which is important to human health. The screening results of newly synthesized compounds will provide a basis for understanding the inhibition of abnormal cell proliferation and activity of osteoclasts in bone resorption during the simultaneous activation of osteoblasts and inhibition of their apoptosis. Product Description popup.authors Брицун Василь Миколайович Зарудницький Євген Вячеславович popup.nrat_date 2020-04-02 Close