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Information × Registration Number 0315U005076, 0115U005360 , R & D reports Title Development and optimization of methods for synthesis and scale-up of aminohydroxybisphosphonates of 4-aminopyrazole analogs popup.stage_title Розробка, оптимізація методів синтезу та напрацювання аміногідроксибісфосфонатів 4 амінопіразолових аналогів Head Volochnyuk Dmytro Mikhalovich, Доктор хімічних наук Registration Date 28-10-2015 Organization Institute of Organic Chemistry National Academy of Sciences of the Ukraine popup.description2 The object of research is the development and optimization of preparative methods of synthesis of aminohydroxybisphosphonates of 4-aminopyrazole analogs. The studies produced results that encourage the development of drugs against osteoporosis, which is important to human health. The screening results of newly synthesized compounds will provide a basis for understanding the inhibition of abnormal cell proliferation and activity of osteoclasts in bone resorption during the simultaneous activation of osteoblasts and inhibition of their apoptosis. Product Description popup.authors Брицун Василь Миколайович Сібгатулін Дмитро Олександрович popup.nrat_date 2020-04-02 Close