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Information × Registration Number 0316U004038, 0115U004346 , R & D reports Title Biosafety and efficiency of interaction of inert metals nanoparticles with bone marrow of mesenchymal stem cells popup.stage_title Визначення біобезпеки та цитотоксичного впливу наночастинокзолота на моношаровій та сфероїдній культурі пухлинних клітин. Head Sydorenko Mychail V., Registration Date 28-04-2016 Organization Department of Biotechnical Problems of Diagnostics, Institute of Problems of Cryobiology and Cryomedicine of NAS of Ukraine popup.description2 Abstract.Gold nanostructure in concentrations of 1.0 to 7.0 micrograms/ml did not affect the viability of HT29 tumor cell lines in the adhesive fraction. Disperse nanogold proportion with increasing concentrations density change of focal cell contacts in HT culture medium and the substrate 29 to stimulate an increase in the number of tumor cells suspension the fraction. Increasing the concentration of gold nanostructured from 1.0 to 7.0 micrograms/ml decreased the volume of cell spheroids obtained from 7.18?10-3 mm3 to 4.95?10-3mm3 , which is accompanied by an increase in their number. Increasing the concentration of carbon nanotubes from 1.0 to 7.0 micrograms/ml, in contrast, stimulated formation of small amounts of tumor spheroids large volume from 4.0 to 6.8 ? 10-3 mm3. The data confirmed the statistical definition of the Pearson correlation coefficient. For nanogold dependence of the volume of multicellular spheroids of concentration is the inverse of -0.48, and for single-walled nanotubes direct +0.82. Product Description popup.authors Безуглий С.В. Вдовиченко Н.О. Перепелиціна О.М. Сидоренко Михайло Васильвич Якимчук О.М. Ястребова О.В. popup.nrat_date 2020-04-02 Close