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Information × Registration Number 0399U002980, 0199U002235 , R & D reports Title Cytogenetic criteria for radiation effects assessment in oncological patients during radiation therapy. popup.stage_title Вивчити загальні зміни цитогенетичних показників у онкологічних хворих під час дистанційної променевої терапії раку молочної залози. Head Maznik N.O., Registration Date 03-06-2000 Organization Grigor'ev Institut for Medical Radiology popup.description2 Object: genome of peripheral blood lymphocytes in patients with mammal cancer undergoing radiation therapy. Aim: To assess the cytogenetic criteria informativity for fractionated partial-body irradiation effects detection in cancer patients at different steps of radiation therapy course. Methods and equipment: cytogenetic analysis of peripheral blood lymphocytesd culture; common statistics; light microscopes Biolam-I, MBI-6. Results: The initial values of chromosomal exchange aberrations level and aneuploid cells yield were found to be increased in patients in compare with healthy persons; chromosomal and chromatide fragments frequencies in cancer patients did not have the significant difference with controls. The qualitive and quantative changes in chromosomal aberration yields in cancer patients during the distant radiation therapy course were measured. Novelty: The initial pre-treatment cytogenetic damage yields were studied in patients with mammal cancer. Application fields: Medicine, radiobiolo gy, oncology, radiation therapy. Product Description popup.authors popup.nrat_date 2020-04-03 Close