Total number
Full text
Total number
Full text
Number of local repositories
Full text
0400U000312,
к.б.н.
24-01-2000
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The lipid membrane homeostasis system in the conditions of oxydative stress, caused by cobalt ions
Shalamov Ruslan Vasyl'ovych,
popup.head Каліман П. А.
popup.opponent Дмитренко М. П.
popup.opponent Мхітарян Л. С.
Об'єкт дослідження: ліпіди печінки, крові, серця, сім'яників, селезінки. Дослідити вплив оксидативного стресу на ліпідний склад органів. Використані методи: тонкошарова хроматографія, диск-електрофорез, турбідиметричний. Показано, що оксидативний стрес, не викликає змін у ліпідному складі мікросомальної фракції печінки. Підвищення вмісту загальних ліпідів у гомогенаті печінки відбувається за рахунок лізосомально-мітохондріальної фракції. При оксидативному стресі на фоні дії інгібіторів транскрипції та трансляції підвищується вміст вільного холестеролу, моно- і триацилгліцеролів, а також різко знижується вміст ефірів холестеролу у гомогенаті печінки. Сфера використання: установи медико-біологічного профілю.
2000-01-24
2020-04-04
Updated: 2025-12-07
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