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0407U002608,
к.б.н.
06-06-2007
o
3. Influence of immunostimulators on immune bodies of dogs in radioactive contamination condition
Dunaevka Oksana Feliksivna,
popup.head Goralsky Leonid Petrovich
popup.opponent Квітницька-Рижова Тетяна Юріївна
popup.opponent Клименко Олег Миколайович
Проведено гістологічні, гістохімічні, морфометричні, радіологічні дослідження тиму-са, лімфатичних вузлів (нижньощелепних, пове-рхневих шийних), селезінки собак двох вікових груп (2-х місячних та 2-х річних). В імунних органах та периферичній крові собак, вироще-них в зоні гарантованого добровільного відсе-лення, виявлені певні зміни: зменшення площі лімфоїдної тканини, зниження рівня імуногло-булінів, відхилення у величинах абсолютних та відносних морфометричних показників, які в комплексі можуть призвести до розвитку вто-ринного імунодефіцитного стану. Гістострукту-ра імунокомпетентних органів після застосуван-ня імуностимуляторів не змінювалась. При цьо-му відбувається незначне збільшення відносної площі кіркової речовини у тимусі, лімфоїдної тканини лімфатичних вузлів. В сироватці крові спостерігається тенденція до зростання кількос-ті імуноглобулінів та фагоцитарної активності. Ключові слова: тимус, лімфовузли, селезінка, імуностимулятори, гамавіт, імунофан, іонізуюче випромінювання, гістологічнедослідження.
2007-06-06
2020-04-04
Updated: 2025-12-08
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