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0410U000638,
к.фарм.н.
19-02-2010
o
Synthesis, physicochemical and biological properties of 1,8-disubstituted theobromine
Ivanchenko Dmitry Grigoryevich,
popup.head Romanenko Mykola Ivanovych
popup.opponent Омельянчик Людмила Олександрівна
popup.opponent Ісаєв Сергій григорович
Основною метою роботи був синтез нових високоефективних та малотоксичних 1,8-дизаміщених теоброміну з потенційною діуретичною, антиоксидантною, анальгетичною та протизапальною активністю, встановлення закономірностей зв'язку між хімічною будовою і біологічною дією, а також відбір сполук з найвищою біологічною активністю для подальших поглиблених доклінічних випробувань.
2010-02-19
2020-04-04
Updated: 2025-12-07
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