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0411U002689,
к.мед.н.
18-05-2011
o
Specific characteristics of the course and treatment of pancreatogenic peritonitis
Kharabara Оleg Havrilovich,
popup.head Polianskyi Igor Yuliiovych
popup.opponent Кулачек Федор Григорьевич
popup.opponent Годлевський Аркадий Иванович
Об'єкт - гострий деструктивний панкреатит ускладнений панкреатогенним перитонітом; мета - вивчити особливості патогенезу, розвитку та перебігу гострого перитоніту як ускладнення деструктивного панкреатиту і розробити на цій основі інформативні методи діагностики, ефективні методи лікування та профілактики; методи - загальноклінічні, лабораторні, інструментальні, мікробіологічні та статистично-аналітичні; результати - в експерименті досліджені провідні ланки патогенезу панкреатогенного перитоніту: джерела та механізми утворення ендотоксинів, шляхи їхнього розповсюдження, умови та механізми генералізації, роль у цих процесах ферментів підшлункової залози, на експериментальній моделі доведено, що перитонеосорбція з використанням сорбентів із наведеними антиферментними та антимікробними властивостями є ефективним методом лікування панкреатогенного перитоніту, упроваджено в клініку розроблені методи перитонеосорбції у хворих на панкреатогенний перитоніт та оцінена ефективність їх використання, запропоновано алгоритм лікувальної тактики у хворих на панкреатогенний перитоніт, результатом застосування нової тактики лікування є зниження показників післяопераційної летальності та ускладнень.
2011-05-18
2020-04-04
Updated: 2025-12-07
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